Agenda

1st ANNUAL BAY AREA STEM CELL CONFERENCE

Asilomar Conference Grounds

 May 8th 2:00 PM - May 11th 1:00 PM, 2019

 

Wednesday, May 8th

 

1:15 - 2:00 PM                        Pre-Meeting Registration

2:00 - 3:00 PM                        Check-In; Merrill Hall

3:00 - 3:05 PM                        Introductory Remarks - Irving Weissman; Merrill Hall

 

Session 1: Hematopoiesis

Moderator: Alma-Martina Cepika

 Location: Merrill Hall

 

3:05 – 3:30 PM                       Talk 1: Amira Barkal - Weissman Lab, Stanford University, “How to Train Your Macrophage: Boosting Macrophage Appetites for Cancer Immunotherapy”

3:30 – 3:55 PM                       Talk 2: Donna Poscablo - Forsberg Lab, UCSC, “Hematopoietic Differentiation Paths During Aging”

3:55 – 4:10 PM                       Break; Merrill Hall

4:10 – 4:35 PM                       Talk 3: Wei-Chieh Mu – Chen Lab, UCB, “Mitochondrial Stress-initiated NLRP3 Inflammasome Activation Regulates Hematopoietic Stem Cell Aging”

4:35 – 5:00 PM                       Talk 4: Sean Corcoran - Bruckner Lab, UCSF, “Regulation of Blood Cell Transdifferentiation by Sensory Neuron Activity”

  

 

Session 2: Fibrosing Diseases and Inflammatory Response

Moderator: Gerlinde Wernig

Location: Merrill Hall

 

5:00 – 5:25 PM                       Talk 5: Tristan Lerbs - Gerlinde Wernig Lab, Stanford University, “JUN drives fibrosis in Lung Fibrosis and Scleroderma by Dampening the Immune Response”

5:25 – 5:50 PM                       Talk 6: Kaitlin Clark - Wang Lab, UCD, “Placental Derived Mesenchymal Stromal/stem cells: Immunomodulatory Properties and Applications for Central Nervous System Inflammation”

6:00 – 7:00 PM                       Dinner; Crocker Hall

Evening Session:

7:30 – 9:30 PM                       Karaoke Reception; Seascape              

 

Thursday, May 9th

 

7:30 - 8:55 AM                        Breakfast; Crocker Hall

8:55 - 9:00 AM                        Introductory Remarks - Rik Derynck; Merrill Hall

 

Session 3: Vascular Development and Regeneration

Moderator: Lindsay Hinck

Location: Merrill Hall

 

9:00 - 9:25 AM                       Talk 1: Brian Raftrey - Red-Horse Lab, Stanford University, “The Transcription Factor Dach1 Promotes Artery Cell Specification During Vascular Development”

9:25 – 9:50 AM                      Talk 2: Juan Pérez-Bermejo - Conklin Lab, Gladstone Institute, “Decoding and Repairing Genetic Disease with CRISPR and iPS Cells

9:50 – 10:15 AM                    Talk 3: Oscar Fernandez-Cazares, Hinck Lab, UCSC, “Robo1 Promotes Mammary Gland Alveologenesis”

10:15 - 10:30 AM                   Break; Merrill Hall

 

Session 4: Pluripotency and Reprogramming

Moderator: Paul Knoepfler

Location: Merrill Hall

 

10:30 – 10:55 AM                  Talk 4: Rachel Klein - Knoepfler Lab, UCD, “Genomic Functions of Dppa4 in Pluripotent and Cancer Cells.”

10:55 – 11:20 AM                  Talk 5: Justyna Janas - Wernig Lab, Stanford University, “Critical Role of the Chromatin Regulator Tip60 in Neuronal Fate Specification” 

11:20 – 11:45 AM                  Talk 6: Roman Reggiardo - Kim Lab, UCSC “Noncoding Transcriptome Dynamics and Heterogeneity in Pluripotency and Cancer”

11:45 - 12:10 PM                   Talk 7: Marianne Goodwin - Alma-Martina Cepika on behalf of the Roncarolo and Bacchetta Labs, Stanford University, “CRISPR-Based Therapy for IPEX Syndrome as a Model of Genetic Autoimmunity.

12:10 - 1:10 PM                     Lunch; Crocker Hall

1:10 - 4:00 PM                       Free Afternoon; Please See Our Website for Suggested Activities

 

Session 5: Epigenetics of Stem Cells

Moderator: Joanna Wysocka

Location: Merrill Hall

 

4:00 - 4:25 PM                        Talk 8: Chad Cockrum - Strome Lab, UCSC, “Single-Cell 8 RNA-seq Profiling of Hand-Dissected C. Elegans Primordial Germ Cells from Wild Type and Mutants” 

4:25 – 4:50 PM                       Talk 9: Michael Song - Shen Lab, UCSF “Charting Cell-Specific 3D Epigenomes During Corticogenesis to Understand Human Brain Development and Complex Disorders”

4:50 – 5:15 PM                       Talk 10: Hannah Long - Wysocka Lab, Stanford University, “Enhancer Loss as a Driver of Human Craniofacial Disorders”                                              

5:15 – 5:40 PM                       Talk 11: Julian Halmai - Fink Lab, UCD, “CRISPR/dCas9-Mediated Escape from X-Chromosome Inactivation in CDKL5 Deficiency Disorder”

5:40 – 6:05 PM                       Talk 12: Jason Fernandes - Haussler/Salama Lab, UCSC, “Evolutionary Arms Races Impact Human Pluripotent Stem Cells”

6:05 - 7:05 PM                        Dinner; Crocker Hall

 

Evening Session:

7:10 - 7:15 PM                        Introductory Remarks - Arnold Kriegstein

7:15 – 8:15 PM                       Keynote Address: Bob Klein, President of Klein Financial Corporation                             

8:15 – 8:30 PM                       Question & Answer Session with Keynote Speaker

8:30 – 10:30 PM                     Poster Presentation Contest/Reception

 

Friday, May 10th

 

7:30 - 8:55 AM                        Breakfast; Crocker Hall

8:55 - 9:00 AM                        Introductory Remarks - Marius Wernig; Merrill Hall

 

Session 6: Next Generation Cell Therapies

Moderator: Camilla Forsberg

Location: Merrill Hall

 

9:00 - 9:25 AM                      Talk 1: Quoc-Hung "Key” Nguye- Mackenzie Lab, UCSF, “In Utero Enzyme Replacement and Stem Cell Transplantation in Murine Sly Syndrome”

9:25 – 9:50 AM                      Talk 2: Alana Horowitz - Villeda Lab, UCSF, “Circulating Blood Factors Transfer the Rejuvenating Effects of Exercise on the Aged Mouse Brain”

9:50 – 10:15 AM                    Talk 3: Peter Deng - Segal Lab, UCD, “Mesenchymal Stem Cell Biofactories for Neurologic Disease”

10:15 - 10:30 AM                   Break; Merrill Hall

 

Session 7: Developmental Principles of Stem Cells

Moderator: Julie Sneddon

Location: Merrill Hall

 

10:30 – 10:55 AM                  Talk 4: Daniel M. Wong - Sneddon Lab, UCSF, “Lineage Dynamics of Pancreatic Endocrine Development at Single-Cell Resolution”  

10:55 - 11:20 AM                   Talk 5: Johannes Schoeneberg - Drubin and Betzig Labs, UCB, “4D Cell Biology: Big Data Image Analytics and Lattice Light-Sheet Imaging of Live Human Stem Cell-Derived Organoids”

11:20 – 11:45 AM                  Talk 6: Jonas Fowler Loh Lab, Stanford University, “How do Human Blood Stem Cells Develop and Can We Recreate them from Pluripotent Cells?”

11:45 – 12:10 PM                  Talk 7: Akela Kuwahara - Bush Lab, UCSF, “Transcriptional Regulation of Tracheoesophageal Specification and Separation”

12:10 – 1:10 PM                     Lunch; Crocker Hall

1:10 -1:35 PM                        Talk 8: G. Bikem Soygur - Laird Lab, UCSF, “Social Interactions Between Fetal Germ Cells”

 

Session 8: Bone, Cartilage, and Muscle-forming Stem Cells

Moderator: Michael Longaker

Location: Merrill Hall

 

1:35 – 2:00 PM                       Talk 9: Susan Eliazer - Brack Lab, UCSF, “Niche Regulation of Muscle Stem Cell Quiescence” 

2:00 – 2:25 PM                       Talk 10: Tom Ambrosi - Chan Lab, Stanford University, ”Deciphering Heterogeneity and Rejuvenating Function of Skeletal Stem Cells”

2:25 – 2:50 PM                       Talk 11: Kara McKinley - Vale/Klein Labs, UCSF, “Patterning Principles of the Mammalian Small Intestine”

2:50 – 3:15PM                        Talk 12: Ying Yang - Reiter Lab, UCSF, “Ciliary Signaling Controls Mechanical Tissue Properties and Organ Growth”

3:15 – 3:30 PM                       Break; Merrill Hall  

 

Session 9: Cell Evolution During Development and Adulthood

Moderator: Holger Willenbring

Location: Merrill Hall

 

3:30 - 3:55 PM                       Talk 13: Jayakrishnan Gopakumar - Jaiswal Lab, Stanford University, “Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease”

3:55 – 4:20 PM                       Talk 14: Corrigan Horton - Wang Lab, UCSC, “Analysis of Prostate Basal Cell Plasticity at the Single Cell Level”

4:20 – 4:45 PM                       Talk 15: Simone Kurial - Willenbring Lab, UCSF, “Therapeutic Transdifferentiation in the Liver”

4:45 – 5:10 PM                       Talk 16: Aparna Bhadhuri - Kriegstein Lab, UCSF, “Outer Radial Glia-like Cells are Invasive Tumor Propagating Cells in Glioblastoma”

5:10 – 5:35 PM                       Talk 17: Marta Losa Llabata - Selleri Lab, UCSF, “Short Tales of Making Faces: Disentangling the Heterogeneity of the Cephalic Epithelium”

5:35 - 6:00 PM                        Free Time

6:00 - 7:00 PM                        Dinner; Merrill Hall

 

Evening Session:

7:00 - 7:05 PM                        Introductory Remarks - Arnold Kriegstein

7:05 – 8:05 PM                       Keynote Address: Jonah Cool, Science Program Officer for the Chan Zuckerberg Initiative

8:05 - 8:20 PM                        Question & Answer Session with Keynote Speaker

8:20 – 10:00 PM                     Bonfire; BBQ Area

 

Saturday, May 11th

 

7:30 - 8:55 AM                        Breakfast; Crocker Hall

8:55 - 9:00 AM                        Introductory Remarks - Camilla Forsberg

 

Session 10: Wound Healing and Tissue Response

Moderator: Josh Stuart

Location: Merrill Hall

 

9:00 - 9:25 AM                      Talk 1: Shamik Mascharak - Longaker Lab, Stanford University, “Regenerative Skin Healing through Targeted Modulation of Engrailed1-negative Fibroblasts”

9:25 – 9:50 AM                      Talk 2: Ashley Libby - McDevitt Lab, UCSF, “Engineering Self-directed Multicellular Organization of Human Pluripotent Stem Cells”

9:50 – 10:15 AM                    Talk 3: Hongxu Ding, postdoc - Stuart Lab, UCSC, “Pathway Transformations Cell Trajectory to Interpret Single Cell RNA-seq Data”

10:15 – 10:30 AM                  Break; Merrill Hall

                                    

 

Session 11: Lung Development and Homeostasis

Moderator: Sarah Knox

Location: Merrill Hall

 

10:30 – 10:55 AM                  Talk 4: Joshua Guild -  Desai Lab, Stanford University, “In Vivo Interrogation of EGF Signaling in Alveolar Maintenance”

10:55 – 11:20 PM                  Talk 5: Alison May - Knox Lab, UCSF, “CFTR is an Essential Regulator of Exocrine Gland Morphogenesis"

11:20 – 11:45 PM                  Talk 6: Jolene Draper - Sanford Lab, UCSC, “mRNA Isoform Fate in Stem Cells”

11:45 – 12:10 PM                    Talk 7: Nabora Soledad Reyes de Mochel - Peng Lab, UCSF, “Physiologically Primed Senescent Mesenchyme Promotes Epithelial Progenitor-Mediated Repair”

12:10 – 12:25 PM                      Closing Remarks - Rik Derynck; Merrill Hall

12:25 PM                                 Boxed Lunches